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KMID : 0363220070450050509
Korean Journal of Dermatology
2007 Volume.45 No. 5 p.509 ~ p.511
Treatment of Acquired Perforating Dermatosis in Chronic Renal Failure with Allopurinol
Park Hai-Jin

Lee Yoo-Shin
Abstract
The perforating disorder is characterized by transepidermal elimination of altered dermal substances, which comprises Kyrle¡¯s disease, perforating folliculitis, elastosis perforans serpiginosa, and reactive perforating collagenosis. The term ¡¯acquired perforating dermatosis¡¯ has been suggested for cases associated with renal disease and/or diabetes mellitus. Recently, resolution of lesions in acquired reactive perforating collagenosis by allopurinol has been reported. We, hereby, report a patient with acquired perforating dermatosis associated with chronic renal failure due to diabetic nephropathy, who was treated with allopurinol. The histopathological findings were compatible with Kyrle¡¯s disease.
KEYWORD
Acquired Perforating Dermatosis, Allopurinol, Kyrle¡¯s disease
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